Expansion of a core regulon by transposable elements promotes Arabidopsis chemical diversity and pathogen defense

Arabidopsis plants can produce 4-hydroxyindole-3-carbonitrile (4OH-ICN) upon pathogen infection. Here, the authors show that EPCOT3, a retrotransposonderived enhancer, mediates WRKY33-binding, pathogen-responsive transcription of CYP82C2, and synthesis of 4OH-ICN.

Bibliographic Details
Main Authors: Brenden Barco, Yoseph Kim, Nicole K. Clay
Format: Article
Language:English
Published: Nature Portfolio 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11406-3