Mis17 is a regulatory module of the Mis6-Mal2-Sim4 centromere complex that is required for the recruitment of CenH3/CENP-A in fission yeast.

Mis17 is a regulatory module of the Mis6-Mal2-Sim4 centromere complex that is required for the recruitment of CenH3/CENP-A in fission yeast.

BACKGROUND: The centromere is the chromosome domain on which the mitotic kinetochore forms for proper segregation. Deposition of the centromeric histone H3 (CenH3, CENP-A) is vital for the formation of centromere-specific chromatin. The Mis6-Mal2-Sim4 complex of the fission yeast S. pombe is require...

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Bibliographic Details
Main Authors: Yoshiharu Shiroiwa, Takeshi Hayashi, Yohta Fujita, Alejandro Villar-Briones, Nobuyasu Ikai, Kojiro Takeda, Masahiro Ebe, Mitsuhiro Yanagida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3061866?pdf=render

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http://europepmc.org/articles/PMC3061866?pdf=render

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