SOX2+ cell population from normal human brain white matter is able to generate mature oligodendrocytes.

OBJECTIVES: A number of neurodegenerative diseases progress with a loss of myelin, which makes them candidate diseases for the development of cell-replacement therapies based on mobilisation or isolation of the endogenous neural/glial progenitor cells, in vitro expansion, and further implantation. C...

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Main Authors: Jorge Oliver-De La Cruz, Josefa Carrión-Navarro, Noemí García-Romero, Antonio Gutiérrez-Martín, Elisa Lázaro-Ibáñez, Carmen Escobedo-Lucea, Rosario Perona, Cristobal Belda-Iniesta, Angel Ayuso-Sacido
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4047120?pdf=render