Cyclin Dependent Kinase Inhibitor 2A Genetic and Epigenetic Alterations Interfere with Several Immune Components and Predict Poor Clinical Outcome

Cyclin Dependent Kinase Inhibitor 2A Genetic and Epigenetic Alterations Interfere with Several Immune Components and Predict Poor Clinical Outcome

Cyclin dependent kinase inhibitor 2A (CDKN2A) is a well-known tumor suppressor gene as it functions as a cell cycle regulator. While several reports correlate the malfunction of CDKN2A with the initiation and progression of several types of human tumors, there is a lack of a comprehensive study that...

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Bibliographic Details
Main Authors: Mohamed A. Soltan, Ahmad A. Alhanshani, Ayed A. Shati, Youssef A. Alqahtani, Dalal Sulaiman Alshaya, Jawaher Alharthi, Sarah Awwadh Altalhi, Eman Fayad, Mohamed Samir A. Zaki, Refaat A. Eid
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomedicines
Subjects:
CDKN2A
differential expression
genetic alteration
epigenetic alteration
patient survival
immunotherapy
Online Access:https://www.mdpi.com/2227-9059/11/8/2254

Internet

https://www.mdpi.com/2227-9059/11/8/2254

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