Prostaglandin E2 Receptor 4 (EP4) as a Therapeutic Target to Impede Breast Cancer-Associated Angiogenesis and Lymphangiogenesis

Prostaglandin E2 Receptor 4 (EP4) as a Therapeutic Target to Impede Breast Cancer-Associated Angiogenesis and Lymphangiogenesis

The formation of new blood (angiogenesis) and lymphatic (lymphangiogenesis) vessels are major events associated with most epithelial malignancies, including breast cancer. Angiogenesis is essential for cancer cell survival. Lymphangiogenesis is critical in maintaining tumoral interstitial fluid bala...

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Bibliographic Details
Main Authors: Guillermo Antonio De Paz Linares, Reid Morgan Opperman, Mousumi Majumder, Peeyush K. Lala
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
breast cancer
triple-negative breast cancer
metastasis
angiogenesis
lymphangiogenesis
COX-2
Online Access:https://www.mdpi.com/2072-6694/13/5/942

Internet

https://www.mdpi.com/2072-6694/13/5/942

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