Evolutionary analysis of Slc11 mechanism of proton-coupled metal-ion transmembrane import

Evolutionary analysis of Slc11 mechanism of proton-coupled metal-ion transmembrane import

Determination of the crystal structure of ScaDMT, a member of the Slc11 family, provided opportunity to advance understanding of proton-dependent metal-ion uptake by interfacing Slc11 molecular evolution and structural biology. Slc11 carriers belong to the ancient and broadly distributed APC superfa...

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Bibliographic Details
Main Author: Mathieu F. M. Cellier
Format: Article
Language:English
Published: AIMS Press 2016-06-01
Series:AIMS Biophysics
Subjects:
metal-ion
membrane transport
proton-coupling
solute carrier family 11
proton-dependent Mn transporter
natural resistance-associated macrophage protein
divalent metal transporter
LeuT fold
amino acid-polyamine-organo-cation superfamily.
Online Access:http://www.aimspress.com/biophysics/article/810/fulltext.html

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http://www.aimspress.com/biophysics/article/810/fulltext.html

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