Protective Effects of High-Fat Diet against Murine Colitis in Association with Leptin Signaling and Gut Microbiome

Protective Effects of High-Fat Diet against Murine Colitis in Association with Leptin Signaling and Gut Microbiome

Inflammatory bowel disease (IBD) is characterized by chronic intestinal-tract inflammation with dysregulated immune responses, which are partly attributable to dysbiosis. Given that diet plays a critical role in IBD pathogenesis and progression, we elucidated the effects of a high-fat diet (HFD) fee...

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Bibliographic Details
Main Authors: Yun-Ha Lee, Hyeyoon Kim, Sorim Nam, Jae-Ryang Chu, Jung-Hwan Kim, Jong-Seok Lim, Sung-Eun Kim, Mi-Kyung Sung
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Life
Subjects:
inflammatory bowel disease
high-fat diet
leptin
intestinal epithelial cell
colonic barrier function
immune response
Online Access:https://www.mdpi.com/2075-1729/12/7/972

Internet

https://www.mdpi.com/2075-1729/12/7/972

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