Dextran sodium sulfate (DSS) induces colitis in mice by forming nano-lipocomplexes with medium-chain-length fatty acids in the colon.

Inflammatory bowel diseases (IBDs), primarily ulcerative colitis and Crohn's disease, are inflammatory disorders caused by multiple factors. Research on IBD has often used the dextran sodium sulfate (DSS)-induced colitis mouse model. DSS induces in vivo but not in vitro intestinal inflammation....

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Bibliographic Details
Main Authors: Hamed Laroui, Sarah A Ingersoll, Hong Chun Liu, Mark T Baker, Saravanan Ayyadurai, Moiz A Charania, Famina Laroui, Yutao Yan, Shanthi V Sitaraman, Didier Merlin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3302894?pdf=render