Application of perturbation gene expression profiles in drug discovery—From mechanism of action to quantitative modelling
High dimensional characterization of drug targets, compound effects and disease phenotypes are crucial for increased efficiency of drug discovery. High-throughput gene expression measurements are one of the most frequently used data acquisition methods for such a systems level analysis of biological...
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| 格式: | 文件 |
| 语言: | English |
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Frontiers Media S.A.
2023-02-01
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| 丛编: | Frontiers in Systems Biology |
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| 在线阅读: | https://www.frontiersin.org/articles/10.3389/fsysb.2023.1126044/full |