Evaluation and Determination of a Suitable Passage Number of Codon Pair Deoptimized PRRSV-1 Vaccine Candidate in Pigs

Evaluation and Determination of a Suitable Passage Number of Codon Pair Deoptimized PRRSV-1 Vaccine Candidate in Pigs

Porcine reproductive and respiratory syndrome virus (PRRSV) is major economic problem given its effects on swine health and productivity. Therefore, we evaluated the genetic stability of a codon pair de-optimized (CPD) PRRSV, E38-ORF7 CPD, as well as the master seed passage threshold that elicited a...

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Bibliographic Details
Main Authors: Min-A Lee, Su-Hwa You, Usharani Jayaramaiah, Eun-Gyeong Shin, Seung-Min Song, Lanjeong Ju, Seok-Jin Kang, Sun-Hee Cho, Bang-Hun Hyun, Hyang-Sim Lee
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Viruses
Subjects:
PRRSV-1
codon pair deoptimization
ORF7
genetic stability
vaccine
Online Access:https://www.mdpi.com/1999-4915/15/5/1071

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https://www.mdpi.com/1999-4915/15/5/1071

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