AAV-mediated expression of HLA-G for the prevention of experimental ocular graft vs. host disease

AAV-mediated expression of HLA-G for the prevention of experimental ocular graft vs. host disease

Ocular graft versus host disease (OGvHD) develops after allogeneic hematopoietic stem cell transplantation (HSCT) and manifests as ocular surface inflammatory disease. This study evaluated the efficacy of adeno-associated virus (AAV) gene therapy encoding human leukocyte antigen G (HLA-G) to inhibit...

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Bibliographic Details
Main Authors: Jacob P. Nilles, Darby Roberts, Jacklyn H. Salmon, Liujiang Song, Carly O’Dea, Lindsay T. Marjoram, Jacquelyn J. Bower, Matthew L. Hirsch, Brian C. Gilger
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
ocular
graft vs. host disease
gene therapy
HLA-G
mouse
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050123000487

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http://www.sciencedirect.com/science/article/pii/S2329050123000487

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