Identification of a soluble guanylate cyclase in RBCs: preserved activity in patients with coronary artery disease

Identification of a soluble guanylate cyclase in RBCs: preserved activity in patients with coronary artery disease

Endothelial dysfunction is associated with decreased NO bioavailability and impaired activation of the NO receptor soluble guanylate cyclase (sGC) in the vasculature and in platelets. Red blood cells (RBCs) are known to produce NO under hypoxic and normoxic conditions; however evidence of expression...

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Bibliographic Details
Main Authors: Miriam M. Cortese-Krott, Evanthia Mergia, Christian M. Kramer, Wiebke Lückstädt, Jiangning Yang, Georg Wolff, Christina Panknin, Thilo Bracht, Barbara Sitek, John Pernow, Johannes-Peter Stasch, Martin Feelisch, Doris Koesling, Malte Kelm
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717306535

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http://www.sciencedirect.com/science/article/pii/S2213231717306535

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