Advances in mechanism of nicotine addiction

Advances in mechanism of nicotine addiction

Nicotine(NIC) plays a role in the brain through nicotinic acetylcholine receptors(nAChRs). nAChRs are ligand-gated ion channel composed of five transmembrane subunits. Mammals contain nine α subunits (α2～α10) and three β subunits (β2～β4). The α4 and the nAChRs subtype of β2 subunit (α4β2-nAChR), in...

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Bibliographic Details
Main Author: JIAO Yang, JIA Ying, ZHU Ping, ZHANG Qian, MA Xiao-li
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2021-07-01
Series:Jichu yixue yu linchuang
Subjects:
nicotinic acetylcholine receptors(nachrs)|cholinergic anti-inflammatory pathway|nicotine|addiction|mesolim-bic system
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a201323.pdf

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http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a201323.pdf

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