ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development
To determine the roles of endoplasmic reticulum (ER) stress and trained immunity, we performed transcriptome analyses on the thoracic aorta (TA) and abdominal aorta (AA) from the angiotensin II (Ang II)-HFD-ApoE-KO aneurysm model and made significant findings: 1) Ang II bypassed HFD-induced metaboli...
Hauptverfasser: | , , , , , , , , , , , , , |
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Format: | Artikel |
Sprache: | English |
Veröffentlicht: |
Frontiers Media S.A.
2023-09-01
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Schriftenreihe: | Frontiers in Immunology |
Schlagworte: | |
Online Zugang: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1268916/full |