Synergistic effect of cryptotanshinone and temozolomide treatment against human glioblastoma cells

Abstract Glioblastoma multiforme (GBM) is a complex disease to treat owing to its profound chemoresistance. Therefore, we evaluated the combined effect and therapeutic efficacy of temozolomide (TMZ), a potent alkylating agent and the current gold standard therapy for GBM, and cryptotanshinone (CTS),...

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Bibliographic Details
Main Authors: Songxian Zhu, Jingjing Guo, Li Yu, Jun Liu, Jixiang Chen, Jinxin Xin, Yuqiang Zhang, Jie Luo, Chao Duan
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48777-z