How to perform meaningful estimates of genetic effects.

Although the genotype-phenotype map plays a central role both in Quantitative and Evolutionary Genetics, the formalization of a completely general and satisfactory model of genetic effects, particularly accounting for epistasis, remains a theoretical challenge. Here, we use a two-locus genetic syste...

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Bibliographic Details
Main Authors: José M Alvarez-Castro, Arnaud Le Rouzic, Orjan Carlborg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2320976?pdf=render