Circulating Neurofilament Light Chain Levels Increase with Age and Are Associated with Worse Physical Function and Body Composition in Men but Not in Women

Circulating Neurofilament Light Chain Levels Increase with Age and Are Associated with Worse Physical Function and Body Composition in Men but Not in Women

This study aimed to assess the relationship between age-related changes in Neurofilament Light Chain (NFL), a marker of neuronal function, and various factors including muscle function, body composition, and metabolomic markers. The study included 40 participants, aged 20 to 85 years. NFL levels wer...

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Bibliographic Details
Main Authors: Xavier Capo, Aina Maria Galmes-Panades, Cayetano Navas-Enamorado, Ana Ortega-Moral, Silvia Marín, Marta Cascante, Andrés Sánchez-Polo, Luis Masmiquel, Margalida Torrens-Mas, Marta Gonzalez-Freire
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
aging
neurodegeneration
metabolomics
NFL
muscle function
gender dimorphism
Online Access:https://www.mdpi.com/1422-0067/24/16/12751

Internet

https://www.mdpi.com/1422-0067/24/16/12751

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