High resolution molecular and histological analysis of renal disease progression in ZSF1 fa/faCP rats, a model of type 2 diabetic nephropathy.

High resolution molecular and histological analysis of renal disease progression in ZSF1 fa/faCP rats, a model of type 2 diabetic nephropathy.

ZSF1 rats exhibit spontaneous nephropathy secondary to obesity, hypertension, and diabetes, and have gained interest as a model system with potentially high translational value to progressive human disease. To thoroughly characterize this model, and to better understand how closely it recapitulates...

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Bibliographic Details
Main Authors: Ken Dower, Shanrong Zhao, Franklin J Schlerman, Leigh Savary, Gabriela Campanholle, Bryce G Johnson, Li Xi, Vuong Nguyen, Yutian Zhan, Matthew P Lech, Ju Wang, Qing Nie, Morten A Karsdal, Federica Genovese, Germaine Boucher, Thomas P Brown, Baohong Zhang, Bruce L Homer, Robert V Martinez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5529026?pdf=render

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http://europepmc.org/articles/PMC5529026?pdf=render

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