The oxidative folding of nascent polypeptides provides electrons for reductive reactions in the ER

The oxidative folding of nascent polypeptides provides electrons for reductive reactions in the ER

Summary: The endoplasmic reticulum (ER) maintains an oxidative redox environment that is advantageous for the oxidative folding of nascent polypeptides entering the ER. Reductive reactions within the ER are also crucial for maintaining ER homeostasis. However, the mechanism by which electrons are su...

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Bibliographic Details
Main Authors: Kaiku Uegaki, Yuji Tokunaga, Michio Inoue, Seiji Takashima, Kenji Inaba, Koh Takeuchi, Ryo Ushioda, Kazuhiro Nagata
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Cell Reports
Subjects:
CP: Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723007532

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http://www.sciencedirect.com/science/article/pii/S2211124723007532

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