Efficacy of otilonium bromide in irritable bowel syndrome: a pooled analysis

Background: Otilonium bromide (OB) is a spasmolytic agent acting as an L-type calcium channel antagonist in intestinal and colonic smooth muscle cells (SMCs). We analyzed three independent clinical trials with homogeneous design on patients with irritable bowel syndrome (IBS). After 2 weeks receivin...

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Bibliographic Details
Main Authors: Pere Clavé, Jan Tack
Format: Article
Language:English
Published: SAGE Publishing 2017-03-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756283X16681708