Downregulation of STK4 promotes colon cancer invasion/migration through blocking β‐catenin degradation

Downregulation of STK4 promotes colon cancer invasion/migration through blocking β‐catenin degradation

Mammalian STE20‐like kinase 1 (MST1/STK4/KRS2) encodes a serine/threonine kinase that is the mammalian homolog of Drosophila Hippo. STK4 plays an important role in controlling cell growth, apoptosis, and organ size. STK4 has been studied in many cancers with previous studies indicating an involvemen...

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Bibliographic Details
Main Authors: Cheng‐Han Lin, Tai‐I Hsu, Pei‐Yu Chiou, Michael Hsiao, Wen‐Ching Wang, Yu‐Chia Chen, Jen‐Tai Lin, Jaw‐Yuan Wang, Peng‐Chan Lin, Forn‐Chia Lin, Yu‐Kai Tseng, Hui‐Chuan Cheng, Chi‐Long Chen, Pei‐Jung Lu
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Molecular Oncology
Subjects:
colon cancers
STK4
β‐catenin
Online Access:https://doi.org/10.1002/1878-0261.12771

Internet

https://doi.org/10.1002/1878-0261.12771

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