Knockdown of miR-660 protects nucleus pulposus cells from TNF-a-induced apoptosis by targeting serum amyloid A1

Knockdown of miR-660 protects nucleus pulposus cells from TNF-a-induced apoptosis by targeting serum amyloid A1

Abstract Background Intervertebral disc degeneration (IVDD) is a well-known cause of lower back pain, which is induced by multiple factors including increased apoptosis and decreased survival of nucleus pulposus cells. In this study, we evaluate the effect and potential mechanism of miR-660 on the n...

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Bibliographic Details
Main Authors: Hao Jie Zhang, Xue Hai Ma, Song Lin Xie, Shu lian Qin, Cong Zhi Liu, Zhen Guo Zhang
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
MicroRNA
Apoptosis
Nucleus pulposus cell
Serum amyloid A1
Online Access:https://doi.org/10.1186/s13018-019-1538-6

Internet

https://doi.org/10.1186/s13018-019-1538-6

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