Stim-activated TRPC-ORAI channels in pulmonary hypertension induced by chronic intermittent hypoxia

Obstructive sleep apnea (OSA), a breathing disorder featured by chronic intermittent hypoxia (CIH) is associated with pulmonary hypertension (PH). Rodents exposed to CIH develop pulmonary vascular remodeling and PH, but the pathogenic mechanisms are not well known. Overexpression of Stim-activated T...

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Bibliographic Details
Main Authors: Sebastian Castillo-Galán, German A. Arenas, Roberto V. Reyes, Bernardo J. Krause, Rodrigo Iturriaga
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045894020941484