Diastereomer-specific quantification of bioactive hexosylceramides from bacteria and mammals[S]

Diastereomer-specific quantification of bioactive hexosylceramides from bacteria and mammals[S]

Mammals synthesize, cell-type specifically, the diastereomeric hexosylceramides, β-galactosylceramide (GalCer) and β-glucosylceramide (GlcCer), which are involved in several diseases, such as sphingolipidosis, diabetes, chronic kidney diseases, or cancer. In contrast, Bacteroides fragilis, a member...

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Bibliographic Details
Main Authors: Johanna von Gerichten, Kerstin Schlosser, Dominic Lamprecht, Ivan Morace, Matthias Eckhardt, Dagmar Wachten, Richard Jennemann, Hermann-Josef Gröne, Matthias Mack, Roger Sandhoff
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Journal of Lipid Research
Subjects:
hydrophilic interaction chromatography
electrospray ionization-tandem mass spectrometry
glucosylceramide
glucocerebroside
galactosylceramide
cerebroside
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520310178

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http://www.sciencedirect.com/science/article/pii/S0022227520310178

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