Functionalized Nitroimidazole Scaffold Construction and Their Pharmaceutical Applications: A 1950–2021 Comprehensive Overview

Nitroimidazole represents one of the most essential and unique scaffolds in drug discovery since its discovery in the 1950s. It was K. Maeda in Japan who reported in 1953 the first nitroimidazole as a natural product from <i>Nocardia mesenterica</i> with antibacterial activity, which was...

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Bibliographic Details
Main Authors: Ria Gupta, Sumit Sharma, Rohit Singh, Ram A. Vishwakarma, Serge Mignani, Parvinder Pal Singh
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/15/5/561