The epithelial-mesenchymal transition and the cytoskeleton in bioengineered systems

The epithelial-mesenchymal transition and the cytoskeleton in bioengineered systems

Abstract The epithelial-mesenchymal transition (EMT) is intrinsically linked to alterations of the intracellular cytoskeleton and the extracellular matrix. After EMT, cells acquire an elongated morphology with front/back polarity, which can be attributed to actin-driven protrusion formation as well...

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Bibliographic Details
Main Authors: Susan E. Leggett, Alex M. Hruska, Ming Guo, Ian Y. Wong
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Cell Communication and Signaling
Subjects:
Actin
Vimentin
Cytoskeleton
Collective migration
Extracellular matrix
Online Access:https://doi.org/10.1186/s12964-021-00713-2

Internet

https://doi.org/10.1186/s12964-021-00713-2

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