Identification of two cancer stem cell-like populations in triple-negative breast cancer xenografts

Identification of two cancer stem cell-like populations in triple-negative breast cancer xenografts

Gene expression analysis at the single-cell level by next-generation sequencing has revealed the existence of clonal dissemination and microheterogeneity in cancer metastasis. The current spatial analysis technologies can elucidate the heterogeneity of cell–cell interactions in situ. To reveal the r...

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Bibliographic Details
Main Authors: Jun Nakayama, Hiroko Matsunaga, Koji Arikawa, Takuya Yoda, Masahito Hosokawa, Haruko Takeyama, Yusuke Yamamoto, Kentaro Semba
Format: Article
Language:English
Published: The Company of Biologists 2022-06-01
Series:Disease Models & Mechanisms
Subjects:
breast cancer
cancer
cancer stem cell
spatial transcriptome
xenograft model
scrna-seq
Online Access:http://dmm.biologists.org/content/15/6/dmm049538

Internet

http://dmm.biologists.org/content/15/6/dmm049538

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