Genetic mutations and molecular mechanisms of Fuchs endothelial corneal dystrophy

Abstract Background Fuchs endothelial corneal dystrophy is a hereditary disease and the most frequent cause of corneal transplantation in the worldwide. Its main clinical signs are an accelerated decrease in the number of endothelial cells, thickening of Descemet’s membrane and formation of guttae i...

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Bibliographic Details
Main Authors: Xuerui Liu, Tao Zheng, Chuchu Zhao, Yi Zhang, Hanruo Liu, Liyuan Wang, Ping Liu
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Eye and Vision
Subjects:
Online Access:https://doi.org/10.1186/s40662-021-00246-2