<it>In vivo</it> assessment of the permeability of the blood-brain barrier and blood-retinal barrier to fluorescent indoline derivatives in zebrafish

<it>In vivo</it> assessment of the permeability of the blood-brain barrier and blood-retinal barrier to fluorescent indoline derivatives in zebrafish

<p>Abstract</p> <p>Background</p> <p>Successful delivery of compounds to the brain and retina is a challenge in the development of therapeutic drugs and imaging agents. This challenge arises because internalization of compounds into the brain and retina is restricted by...

Full description

Bibliographic Details
Main Authors: Watanabe Kohei, Nishimura Yuhei, Nomoto Tsuyoshi, Umemoto Noriko, Zhang Zi, Zhang Beibei, Kuroyanagi Junya, Shimada Yasuhito, Shintou Taichi, Okano Mie, Miyazaki Takeshi, Imamura Takeshi, Tanaka Toshio
Format: Article
Language:English
Published: BMC 2012-08-01
Series:BMC Neuroscience
Subjects:
Blood-brain barrier
Blood-retinal barrier
Zebrafish
Fluorescent indoline derivatives
Transporters
Online Access:http://www.biomedcentral.com/1471-2202/13/101

Internet

http://www.biomedcentral.com/1471-2202/13/101

Similar Items