Recombinant BCG expressing the LTAK63 adjuvant induces increased early and long-term immune responses against Mycobacteria

Recombinant BCG expressing the LTAK63 adjuvant induces increased early and long-term immune responses against Mycobacteria

The development of more effective vaccines against Mycobacterium tuberculosis has become a world priority. Previously, we have shown that a recombinant BCG expressing the LTAK63 adjuvant (rBCG-LTAK63) displayed higher protection than BCG against tuberculosis challenge in mice. In order to elucidate...

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Bibliographic Details
Main Authors: Carina Carvalho Dos Santos, Dunia Rodriguez, Alex Kanno Issamu, Luciana Cezar De Cerqueira Leite, Ivan Pereira Nascimento
Format: Article
Language:English
Published: Taylor & Francis Group 2020-03-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
tuberculosis
vaccine
recombinant bcg
innate immunity
long-term immunity
Online Access:http://dx.doi.org/10.1080/21645515.2019.1669414

Internet

http://dx.doi.org/10.1080/21645515.2019.1669414

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