Programmable CRISPR‐Cas transcriptional activation in bacteria

Programmable CRISPR‐Cas transcriptional activation in bacteria

Abstract Programmable gene activation enables fine‐tuned regulation of endogenous and synthetic gene circuits to control cellular behavior. While CRISPR‐Cas‐mediated gene activation has been extensively developed for eukaryotic systems, similar strategies have been difficult to implement in bacteria...

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Bibliographic Details
Main Authors: Hsing‐I Ho, Jennifer R Fang, Jacky Cheung, Harris H Wang
Format: Article
Language:English
Published: Springer Nature 2020-07-01
Series:Molecular Systems Biology
Subjects:
bacterial gene regulation
CRISPR tools
protein engineering
synthetic transcription activator
Online Access:https://doi.org/10.15252/msb.20199427

Internet

https://doi.org/10.15252/msb.20199427

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