SFRP4+IGFBP5hi NKT cells induced neural-like cell differentiation to contribute to adenomyosis pain

SFRP4+IGFBP5hi NKT cells induced neural-like cell differentiation to contribute to adenomyosis pain

BackgroundAdenomyosis is an estrogen-dependent gynecological disease. The pathogenesis of chronic pain, the main clinical symptom of adenomyosis, remains undefined. As a combination lymphocyte with both T-cell and natural killer (NK)–cell properties, NK T (NKT) cells play a role in immune defense ag...

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Bibliographic Details
Main Authors: Yichen Chen, Jue Zhu, Liang Chen, Yuanyuan Shen, Jing Zhang, Qiming Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
adenomyosis pain
single-cell sequencing
neural-like cells
NKT cells
IGFBP5
SFRP4
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.945504/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.945504/full

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