High Expression of CSF-1R Predicts Poor Prognosis and CSF-1Rhigh Tumor-Associated Macrophages Inhibit Anti-Tumor Immunity in Colon Adenocarcinoma

High Expression of CSF-1R Predicts Poor Prognosis and CSF-1Rhigh Tumor-Associated Macrophages Inhibit Anti-Tumor Immunity in Colon Adenocarcinoma

BackgroundColony stimulating factor 1 receptor (CSF-1R) is a single channel III transmembrane receptor tyrosine kinase (RTK) and plays an important role in immune regulation and the development of various cancer types. The expression of CSF-1R in colon adenocarcinoma (COAD) and its prognostic value...

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Bibliographic Details
Main Authors: Xingchao Wang, Jianfeng Zhang, Baoying Hu, Fei Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
CSF-1R
colon adenocarcinoma
prognosis
pathway
tumor immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.850767/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.850767/full

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