Topical Application of a Vitamin A Derivative and Its Combination With Non-ablative Fractional Laser Potentiates Cutaneous Influenza Vaccination

Topical Application of a Vitamin A Derivative and Its Combination With Non-ablative Fractional Laser Potentiates Cutaneous Influenza Vaccination

Skin contains a large number of antigen presenting cells, making intradermal (ID) injection one of the most effective ways for vaccine administration. However, although current adjuvants may cause severe local reactions and inflammations in the skin, no adjuvant has been approved for ID vaccination...

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Bibliographic Details
Main Authors: Peiyu Li, Ji Wang, Miao Cao, Qiwen Deng, Shibo Jiang, Mei X. Wu, Lu Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Microbiology
Subjects:
all-trans retinoic acid
cutaneous adjuvant
influenza vaccine
interferon regulatory factor 3
interferon regulatory factor 7
non-ablative fractional laser
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02570/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.02570/full

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