Correlations between transmembrane 4 L6 family member 5 (TM4SF5), CD151, and CD63 in liver fibrotic phenotypes and hepatic migration and invasive capacities.

Transmembrane 4 L6 family member 5 (TM4SF5) is overexpressed during CCl4-mediated murine liver fibrosis and in human hepatocellular carcinomas. The tetraspanins form tetraspanin-enriched microdomains (TEMs) consisting of large membrane protein complexes on the cell surface. Thus, TM4SF5 may be invol...

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Main Authors: Minkyung Kang, Jihye Ryu, Doohyung Lee, Mi-Sook Lee, Hye-Jin Kim, Seo Hee Nam, Haeng Eun Song, Jungeun Choi, Gyu-Ho Lee, Tai Young Kim, Hansoo Lee, Sang Jick Kim, Sang-Kyu Ye, Semi Kim, Jung Weon Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4102591?pdf=render