Identification of Codon 146 <i>KRAS</i> Variants in Isolated Epidermal Nevus and Multiple Lesions in Oculoectodermal Syndrome: Confirmation of the Phenotypic Continuum of Mosaic RASopathies

Identification of Codon 146 <i>KRAS</i> Variants in Isolated Epidermal Nevus and Multiple Lesions in Oculoectodermal Syndrome: Confirmation of the Phenotypic Continuum of Mosaic RASopathies

Mosaic RASopathies are a molecularly heterogeneous group of (neuro)cutaneous syndromes with high phenotypical variability. Postzygotic variants in <i>KRAS</i> have been described in oculoectodermal syndrome (OES), encephalocraniocutaneous lipomatosis (ECCL) and epidermal nevus syndrome (...

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Bibliographic Details
Main Authors: Aude Beyens, Laure Dequeker, Hilde Brems, Sandra Janssens, Hannes Syryn, Anne D’Hooghe, Pascale De Paepe, Lieve Vanwalleghem, Annelies Stockman, Elena Vankwikelberge, Sofie De Schepper, Marleen Goeteyn, Patricia Delbeke, Bert Callewaert
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
epidermal nevus
oculoectodermal syndrome
encephalocraniocutaneous syndrome
nevus psiloliparus
epibulbar dermoid
<i>KRAS</i>
Online Access:https://www.mdpi.com/1422-0067/23/7/4036

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https://www.mdpi.com/1422-0067/23/7/4036

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