HMG – CoA reductase inhibition mediated hypocholesterolemic potential of myricetin and quercetin: in-silico and in-vivo studies

HMG – CoA reductase inhibition mediated hypocholesterolemic potential of myricetin and quercetin: in-silico and in-vivo studies

ABSTRACTThe study was aimed to examine the HMG-CoA reductase (HMGCR) inhibition potential. The in-silico investigations followed the assessments of molecular docking, druggability and molecular dynamics. The molecular dynamics was performed at 100 ns by calculating interaction free energies, RSMD, R...

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Bibliographic Details
Main Authors: Priyanka Riyad, Ashok Purohit, Karishma Sen, Anil Panwar, Heera Ram
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:CyTA - Journal of Food
Subjects:
HMGCR
myricetin
quercetin
molecular dynamics
antioxidants
hypercholesterolemia
Online Access:https://www.tandfonline.com/doi/10.1080/19476337.2022.2162976

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https://www.tandfonline.com/doi/10.1080/19476337.2022.2162976

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