Classical famous prescription of Jichuan decoction improved loperamide-induced slow transit constipation in rats through the cAMP/PKA/AQPs signaling pathway and maintained inflammatory/intestinal flora homeostasis

Classical famous prescription of Jichuan decoction improved loperamide-induced slow transit constipation in rats through the cAMP/PKA/AQPs signaling pathway and maintained inflammatory/intestinal flora homeostasis

Introduction: Jichuan decoction (JCD) is a well-known traditional Chinese medicinal formula that moistens the intestines and is widely used for the treatment of constipation in China. However, its effects and mechanisms in alleviating slow transit constipation (STC) in vivo remain unclear. We attemp...

Full description

Bibliographic Details
Main Authors: Lina Lin, Yuanyuan Jiang, Pengfei Lin, Lanlan Ge, Haoqiang Wan, Shuwen Dai, Runjing Zhang, Jie Yao, Xiaobin Zeng, Ying Peng
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
Jichuan decoction
Slow transit constipation
cAMP/PKA/AQPs pathway
Inflammation
Intestinal flora homeostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023090783

Internet

http://www.sciencedirect.com/science/article/pii/S2405844023090783

Similar Items