Both chimpanzee adenovirus-vectored and DNA vaccines induced long-term immunity against Nipah virus infection

Abstract Nipah virus (NiV) is a highly lethal zoonotic paramyxovirus that poses a severe threat to humans due to its high morbidity and the lack of viable countermeasures. Vaccines are the most crucial defense against NiV infections. Here, a recombinant chimpanzee adenovirus-based vaccine (AdC68-G)...

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Bibliographic Details
Main Authors: Mingqing Lu, Yanfeng Yao, Xuekai Zhang, Hang Liu, Ge Gao, Yun Peng, Miaoyu Chen, Jiaxuan Zhao, XiaoYu Zhang, Chunhong Yin, Weiwei Guo, Peipei Yang, Xue Hu, Juhong Rao, Entao Li, Tong Chen, Sandra Chiu, Gary Wong, Zhiming Yuan, Jiaming Lan, Chao Shan
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00762-3