Netrin-1 Role in Nociceptive Neuron Sprouting through Activation of DCC Signaling in a Rat Model of Bone Cancer Pain

Netrin-1 Role in Nociceptive Neuron Sprouting through Activation of DCC Signaling in a Rat Model of Bone Cancer Pain

Background: Bone cancer pain (BCP) is a common primary or metastatic bone cancer complication. Netrin-1 plays an essential role in neurite elongation and pain sensitization. This study aimed to determine the role of netrin-1 from the metastatic bone microenvironment in BCP development and identify t...

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Bibliographic Details
Main Authors:	Zhihao Gong, Yuxin Zhang, Wei Wang, Xin Li, Kai Wang, Xingji You, Jingxiang Wu
Format:	Article
Language:	English
Published:	IMR Press 2024-02-01
Series:	Journal of Integrative Neuroscience
Subjects:	bone cancer pain netrin-1 dcc fak rac1/cdc42 cgrp axonal guidance neurite elongation nociception
Online Access:	https://www.imrpress.com/journal/JIN/23/3/10.31083/j.jin2303047

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