Optimising research investment by simulating and evaluating monitoring strategies to inform a trial: a simulation of liver fibrosis monitoring

Abstract Background The aim of the study was to investigate the development of evidence-based monitoring strategies in a population with progressive or recurrent disease. A simulation study of monitoring strategies using a new biomarker (ELF) for the detection of liver cirrhosis in people with known...

Full description

Bibliographic Details
Main Authors: Alice J. Sitch, Jacqueline Dinnes, Jenny Hewison, Walter Gregory, Julie Parkes, Jonathan J. Deeks
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-024-02425-w