Differential transcriptome response of blood brain barrier spheroids to neuroinvasive Neisseria and Borrelia

Differential transcriptome response of blood brain barrier spheroids to neuroinvasive Neisseria and Borrelia

BackgroundThe blood-brain barrier (BBB), a highly regulated interface between the blood and the brain, prevents blood-borne substances and pathogens from entering the CNS. Nevertheless, pathogens like Neisseria meningitidis and Borrelia bavariensis can breach the BBB and infect the brain parenchyma....

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Bibliographic Details
Main Authors: Amod Kulkarni, Jana Jozefiaková, Katarína Bhide, Evelína Mochnaćová, Mangesh Bhide
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
blood-brain barrier
BBB-spheroids
Neisseria meningitidis
Borrelia bavariensis
transcriptome analysis
human BMECs
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1326578/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2023.1326578/full

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