Inferring the Effects of Protein Variants on Protein–Protein Interactions with Interpretable Transformer Representations

Identifying pathogenetic variants and inferring their impact on protein–protein interactions sheds light on their functional consequences on diseases. Limited by the availability of experimental data on the consequences of protein interaction, most existing methods focus on building models to predic...

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Bibliographic Details
Main Authors: Zhe Liu, Wei Qian, Wenxiang Cai, Weichen Song, Weidi Wang, Dhruba Tara Maharjan, Wenhong Cheng, Jue Chen, Han Wang, Dong Xu, Guan Ning Lin
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2023-01-01
Series:Research
Online Access:https://spj.science.org/doi/10.34133/research.0219