EZH2: Its regulation and roles in immune disturbance of SLE

EZH2: Its regulation and roles in immune disturbance of SLE

The pathogenesis of systemic lupus erythematosus (SLE) is related to immune homeostasis imbalance. Epigenetic mechanisms have played a significant role in breaking immune tolerance. Enhancer of zeste homolog 2 (EZH2), the specific methylation transferase of lysine at position 27 of histone 3, is cur...

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Bibliographic Details
Main Authors: Yiying Yang, Ke Liu, Meidong Liu, Huali Zhang, Muyao Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
EZH2
systemic lupus erythematosus
T cells
B cells
immune homeostasis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1002741/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1002741/full

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