Therapeutic drug monitoring of perampanel in children diagnosed with epilepsy: Focus on influencing factors on the plasma concentration‐to‐dose ratio

Therapeutic drug monitoring of perampanel in children diagnosed with epilepsy: Focus on influencing factors on the plasma concentration‐to‐dose ratio

Abstract Objective This study aimed to investigate the efficacy and tolerability of perampanel (PER) therapy and to optimize a specific plasma reference range for PER in children. Another major aim was to evaluate the potential determinators of PER concentration. Methods Concentrations obtained from...

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Bibliographic Details
Main Authors: Yue Li, Na Dong, Yu‐Xin Qin, Hao‐Ran Dai, Ya‐Hui Hu, Yue‐Tao Zhao, Hong‐Li Guo, Yuan‐Yuan Zhang, Jing Chen, Xiao‐Peng Lu, Feng Chen
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Epilepsia Open
Subjects:
children
epilepsy
perampanel
plasma concentration range
therapeutic drug monitoring
Online Access:https://doi.org/10.1002/epi4.12653

Internet

https://doi.org/10.1002/epi4.12653

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