The spontaneous immortalization probability of mammalian cell culture strains, as their proliferative capacity, correlates with species body mass, not longevity

Background: The Peto's paradox consists in the observation that individuals from long-lived and large animal species do not experience a higher cancer incidence, despite being exposed for longer time to the possibility of accumulating mutations and having more target cells exposed to the phenom...

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Bibliographic Details
Main Authors: Matteo Perillo, Angela Punzo, Cristiana Caliceti, Christian Sell, Antonello Lorenzini
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Biomedical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417023000331