Main features of COL4A1-COL4A2 related cerebral microangiopathies

Main features of COL4A1-COL4A2 related cerebral microangiopathies

COL4A1 and COL4A2 genes encode the alpha1 and the alpha2 chains of type IV collagen, a key component of basement membranes. Mutations located in the coding sequence of COL4A1/COL4A2 genes are responsible for an autosomal dominant (AD) cerebral angiopathy that manifest in either adults, children or f...

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Bibliographic Details
Main Authors: Stéphanie Guey, Dominique Hervé
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Cerebral Circulation - Cognition and Behavior
Subjects:
hereditary cerebral small vessel disease
Autosomal dominant
Collagenopathy
Brain hemorrhage
COL4A1
COL4A2
Online Access:http://www.sciencedirect.com/science/article/pii/S2666245022001052

Internet

http://www.sciencedirect.com/science/article/pii/S2666245022001052

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