Serum neurofilament indicates that DBS surgery can cause neuronal damage whereas stimulation itself does not

Serum neurofilament indicates that DBS surgery can cause neuronal damage whereas stimulation itself does not

Abstract Deep brain stimulation (DBS) is a potent symptomatic therapy for Parkinson’s disease, but it is debated whether it causes or prevents neurodegeneration. We used serum neurofilament light chain (NFL) as a reporter for neuronal damage and found no difference between 92 patients with chronic S...

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Bibliographic Details
Main Authors: Anika Frank, Jonas Bendig, Iñaki Schniewind, Witold H. Polanski, Stephan B. Sobottka, Heinz Reichmann, Katja Akgün, Tjalf Ziemssen, Lisa Klingelhoefer, Björn H. Falkenburger
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-05117-x

Internet

https://doi.org/10.1038/s41598-022-05117-x

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