Involvement of NLRP3 and NLRC4 Inflammasome in Uropathogenic E. coli Mediated Urinary Tract Infections

Involvement of NLRP3 and NLRC4 Inflammasome in Uropathogenic E. coli Mediated Urinary Tract Infections

BackgroundInflammatory response during urinary tract infection (UTI) is mediated by innate immune defense. Nod like receptors (NLRs) have been proposed to work simultaneously beside TLR pathways to mediate pro-inflammatory response and maintain tissue homeostasis. Some in vitro reports have showed t...

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Bibliographic Details
Main Authors: Vivek Verma, Surbhi Gupta, Parveen Kumar, Sonal Yadav, Rakesh Singh Dhanda, Rajni Gaind, Renu Arora, Niels Frimodt-Møller, Manisha Yadav
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Microbiology
Subjects:
inflammasomes
nod like receptors (NLR)
NLRP3
NLRC4
uropathogenic Escherichia coli (UPEC)
urinary tract infection (UTI)
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02020/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.02020/full

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