Mouse embryonic kidney transplantation identifies maturation defects in the medulla

Abstract Kidney organoids are connected to the host circulation and mature after transplantation. However, they are still immature compared to the adult kidneys, and their precise maturation stages remain unclear. By transplanting the mouse embryonic kidney as a model system for organoid transplanta...

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Bibliographic Details
Main Authors: Hiroshi Ide, Koichiro Miike, Tomoko Ohmori, Kosuke Maruyama, Yuichiro Izumi, Shunsuke Tanigawa, Ryuichi Nishinakamura
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-81984-w